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Mouse Wee1 Antibody (Center)

Mouse Wee1 Antibody (Center)

Item no.	ABC-AP19012C
Manufacturer	Abcepta
Amount	400 ul
Category	Oncology Antibodies By Cell Type Western Blot Primary Antibodies
Type	Antibody Polyclonal
Applications	WB
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Citations	Muller, M., et al. J. Cell. Sci. 123 (PT 2), 286-294 (2010): Kim, M.J., et al. Oncol. Rep. 19(5):1323-1329(2008) Tanaka, Y., et al. Biochem. Biophys. Res. Commun. 352(1):21-28(2007) Tominaga, Y., et al. Int. J. Biol. Sci. 2(4):161-170(2006) Park, C.E., et al. Cells Tissues Organs (Print) 177(4):221-228(2004)
NCBI	NP_033542.2
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Wee1-like protein kinase,Wee1A kinase,Wee1
Similar products	Wee1, Wee1-like protein kinase, Wee1A kinase
Available
Manufacturer - Category	Primary Antibodies; Cell Biology
Manufacturer - Targets	This Mouse Wee1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 202-230 amino acids from the Central region of mouse Wee1.
Bio Background	Wee1 may act as a negative regulator of entry into mitosis (G2 to M transition) by protecting the nucleus from cytoplasmically activated cyclin B1-complexed CDK1 before the onset of mitosis. Its activity increases during S and G2 phases and decreases at M phase when it is hyperphosphorylated. A correlated decrease in protein level occurs at M/G1 phase, probably due to its degradation. Specifically phosphorylates and inactivates cyclin B1-complexed CDK1 reaching a maximum during G2 phase and a minimum as cells enter M phase. Phosphorylation of cyclin B1-CDK1 occurs exclusively on 'Tyr-15' and phosphorylation of monomeric CDK1 does not occur (By similarity).
Clonality	Polyclonal
Polyclonal Antibody Additonal Information	RB39511
Gene Name	Wee1
Subtitle	Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Predicted Reactivity	Rat
Calculated Molecular Weight	71578
Antigen Source	MOUSE
Antigen Region	202-230
Formulation	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Dilution	WB: 1:1000
Antigen Type	Synthetic Peptide

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 400 ul

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Delivery expected until 3/5/2026

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