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SMPD3 Antibody (N-term)

SMPD3 Antibody (N-term)

Item no.	ABC-AP19071a
Manufacturer	Abcepta
Amount	400 ul
Category	Metabolism Cholesterol & Lipid Metabolism Antibodies Western Blot Enzymes Fatty Acid Catabolism Primary Antibodies
Type	Antibody Polyclonal
Applications	WB
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Citations	Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010) Filosto, S., et al. J. Biol. Chem. 285(14):10213-10222(2010) Maupas-Schwalm, F., et al. Cell. Signal. 21(12):1925-1934(2009) Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009) Ito, H., et al. Biochim. Biophys. Acta 1789 (11-12), 681-690 (2009) :
NCBI	NP_061137.1
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Sphingomyelin phosphodiesterase 3,Neutral sphingomyelinase 2,nSMase-2,nSMase2,Neutral sphingomyelinase II,SMPD3
Similar products	SMPD3, Sphingomyelin phosphodiesterase 3, Neutral sphingomyelinase 2, Neutral sphingomyelinase II, nSMase-2, nSMase2
Available
Manufacturer - Category	Primary Antibodies; Neuroscience
Manufacturer - Targets	This SMPD3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 137-165 amino acids from the N-terminal region of human SMPD3.
Bio Background	SMPD3 catalyzes the hydrolysis of sphingomyelin to form ceramide and phosphocholine. Ceramide mediates numerous cellular functions, such as apoptosis and growth arrest, and is capable of regulating these 2 cellular events independently. Also hydrolyzes sphingosylphosphocholine. Regulates the cell cycle by acting as a growth suppressor in confluent cells. Probably acts as a regulator of postnatal development and participates in bone and dentin mineralization.
Clonality	Polyclonal
Polyclonal Antibody Additonal Information	RB39878
Gene Name	SMPD3
Subtitle	Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Predicted Reactivity	M, Rat
Calculated Molecular Weight	71081
Antigen Source	HUMAN
Antigen Region	137-165
Formulation	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Dilution	WB: 1:1000
Antigen Type	Synthetic Peptide

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 400 ul

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Delivery expected until 1/1/2026

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