Comparison

APH1A Antibody (N-term)

Item no. ABC-AP19161A-ev
Manufacturer Abcepta
Amount 80 ul
Category
Type Antibody Polyclonal
Applications WB
Specific against Mouse (Murine, Mus musculus)
Host Rabbit
Isotype IgG
Citations Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010):
Mitsuishi, Y., et al. J. Biol. Chem. 285(20):14920-14931(2010)
Chen, A.C., et al. J. Biol. Chem. 285(15):11378-11391(2010)
Pardossi-Piquard, R., et al. J. Biol. Chem. 284(24):16298-16307(2009)
Wang, Y., et al. Neurosci. Lett. 455(2):101-104(2009)
NCBI NP_001071096.1,NP_001230700.1,NP_001230701.1,NP_057106.2
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias Gamma-secretase subunit APH-1A,APH-1a,Aph-1alpha,Presenilin-stabilization factor,APH1A,PSF
Similar products PSF, APH1A, Gamma-secretase subunit APH-1A, Aph-1alpha, Presenilin-stabilization factor, APH-1a
Available
Manufacturer - Category
Primary Antibodies; Neuroscience; Signal Transduction
Manufacturer - Targets
This APH1A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 41-70 amino acids from the N-terminal region of human APH1A.
Bio Background
APH1 is a multipass transmembrane protein that interactswith presenilin (see PSEN1; MIM 14311) and nicastrin (APH2; MIM65254) as a functional component of the gamma-secretase complex.The gamma-secretase complex is required for the intramembraneproteolysis of a number of membrane proteins, including theamyloid-beta precursor protein (APP; MIM 1476) and Notch (MIM19198).
Clonality
Polyclonal
Polyclonal Antibody Additonal Information
RB39321
Gene Name
APH1A
Subtitle
Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity
M
Calculated Molecular Weight
28996
Antigen Source
HUMAN
Antigen Region
41-70
Formulation
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Dilution
WB: 1:1000
Antigen Type
Synthetic Peptide

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 80 ul
Available: In stock
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