Comparison

CTNNB1 Antibody(C-term)

Item no. ABC-AP19562b
Manufacturer Abcepta
Amount 400 ul
Category
Type Antibody Polyclonal
Applications WB
Specific against Human (Homo sapiens)
Host Rabbit
Isotype IgG
Citations Huang, W., et al. Mol. Cell. Biol. 30(19):4575-4594(2010)
Chairoungdua, A., et al. J. Cell Biol. 190(6):1079-1091(2010)
Mirza, M.K., et al. J. Exp. Med. 207(8):1675-1685(2010)
Guo, Q., et al. Acta Biochim. Biophys. Sin. (Shanghai) 42(7):450-456(2010)
Teng, Y., et al. Zhonghua Yi Xue Za Zhi 90(14):988-992(2010)
NCBI NP_001091679.1,NP_001091680.1,NP_001895.1
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias Catenin beta-1,Beta-catenin,CTNNB1,CTNNB
Similar products Catenin beta-1, CTNNB1, CTNNB, Beta-catenin
Available
Manufacturer - Category
Primary Antibodies; Cancer; Cardiovascular; Neuroscience; Signal Transduction; Anti-Wnt-Pathway (plus Lgr5) Antibodies
Manufacturer - Targets
This CTNNB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 723-751 amino acids from the C-terminal region of human CTNNB1.
Bio Background
The protein encoded by this gene is part of a complex ofproteins that constitute adherens junctions (AJs). AJs arenecessary for the creation and maintenance of epithelial celllayers by regulating cell growth and adhesion between cells. Theencoded protein also anchors the actin cytoskeleton and may beresponsible for transmitting the contact inhibition signal thatcauses cells to stop dividing once the epithelial sheet iscomplete. Finally, this protein binds to the product of the APCgene, which is mutated in adenomatous polyposis of the colon.Mutations in this gene are a cause of colorectal cancer (CRC), pilomatrixoma (PTR), medulloblastoma (MDB), and ovarian cancer.Three transcript variants encoding the same protein have been foundfor this gene.
Clonality
Polyclonal
Polyclonal Antibody Additonal Information
RB41158
Gene Name
CTNNB1
Subtitle
Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity
H
Predicted Reactivity
B, M, Rat
Calculated Molecular Weight
85497
Antigen Source
HUMAN
Antigen Region
723-751
Formulation
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Dilution
WB: 1:1000
WB: 1:1000
Antigen Type
Synthetic Peptide

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 400 ul
Available: In stock
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