ENPP1 Antibody(N-term)

NP_006199.2

This gene is a member of the ecto-nucleotide
pyrophosphatase/phosphodiesterase (ENPP) family. The encoded
protein is a type II transmembrane glycoprotein comprising two
identical disulfide-bonded subunits. This protein has broad
specificity and cleaves a variety of substrates, including
phosphodiester bonds of nucleotides and nucleotide sugars and
pyrophosphate bonds of nucleotides and nucleotide sugars. This
protein may function to hydrolyze nucleoside 5' triphosphates to
their corresponding monophosphates and may also hydrolyze
diadenosine polyphosphates. Mutations in this gene have been
associated with 'idiopathic' infantile arterial calcification,
ossification of the posterior longitudinal ligament of the spine
(OPLL), and insulin resistance.

5167

H

6-34

This ENPP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 6-34 amino acids from the N-terminal region of human ENPP1.