Comparison

EGFR Antibody (N-term)

Item no. ABC-AP19833a
Manufacturer Abcepta
Amount 400 ul
Category
Type Antibody Polyclonal
Applications WB, IHC-P
Specific against Human (Homo sapiens)
Host Rabbit
Isotype IgG
Citations Abdallah, R.T., et al. J. Biol. Chem. 285(45):35206-35215(2010)
Lu, C., et al. Mol. Cell. Biol. 30(22):5432-5443(2010)
Rosell, R., et al. Ann. N. Y. Acad. Sci. 1210, 45-52 (2010):
Hata, A., et al. J Thorac Oncol 5(10):1524-1528(2010)
Aguirre, A., et al. Nature 467(7313):323-327(2010)
NCBI NP_005219.2,NP_958439.1,NP_958440.1,NP_958441.1
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias Epidermal growth factor receptor,Proto-oncogene c-ErbB-1,Receptor tyrosine-protein kinase erbB-1,EGFR,ERBB,ERBB1,HER1
Similar products EGFR, ERBB, ERBB1, HER1, Epidermal growth factor receptor, Proto-oncogene c-ErbB-1, Receptor tyrosine-protein kinase erbB-1
Available
Manufacturer - Category
Crown Antibodies; Primary Antibodies; Cancer; Signal Transduction; Anti-Kinome Antibodies
Manufacturer - Targets
This EGFR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 259-287 amino acids from the N-terminal region of human EGFR.
Bio Background
The protein encoded by this gene is a transmembraneglycoprotein that is a member of the protein kinase superfamily.This protein is a receptor for members of the epidermal growthfactor family. EGFR is a cell surface protein that binds toepidermal growth factor. Binding of the protein to a ligand inducesreceptor dimerization and tyrosine autophosphorylation and leads tocell proliferation. Mutations in this gene are associated with lungcancer. Multiple alternatively spliced transcript variants thatencode different protein isoforms have been found for this gene.
Clonality
Polyclonal
Polyclonal Antibody Additonal Information
RB41396
Gene Name
EGFR
Subtitle
Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity
H
Predicted Reactivity
C, M
Calculated Molecular Weight
134277
Antigen Source
HUMAN
Antigen Region
259-287
Formulation
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Dilution
WB: 1:1000
IHC-P: 1:25
Antigen Type
Synthetic Peptide

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 400 ul
Available: In stock
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