MMP14 Antibody (C-term)

Primary Antibodies; Cancer; Cardiovascular; Cell Biology; Metabolism; Signal Transduction; SARS-Human interaction partners

Proteins of the matrix metalloproteinase (MMP) family areinvolved in the breakdown of extracellular matrix in normalphysiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in diseaseprocesses, such as arthritis and metastasis. Most MMP's aresecreted as inactive proproteins which are activated when cleavedby extracellular proteinases. However, the protein encoded by thisgene is a member of the membrane-type MMP (MT-MMP) subfamily; eachmember of this subfamily contains a potential transmembrane domainsuggesting that these proteins are expressed at the cell surfacerather than secreted. This protein activates MMP2 protein, and thisactivity may be involved in tumor invasion.

RB41662

Affinity Purified Rabbit Polyclonal Antibody (Pab)

M, Pig, Rat

HUMAN

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Synthetic Peptide