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BMPR1B Antibody (C-term)

BMPR1B Antibody (C-term)

Item no.	ABC-AP2005B-ev-80ul
Manufacturer	Abcepta
Amount	80 ul
Category	Antibodies Immunohistochemistry Western Blot Primary Antibodies
Type	Antibody Polyclonal
Applications	Western Blot, Immunohistochemistry
Specific against	other
Host	Rabbit
Isotype	Ig
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Bone morphogenetic protein receptor type-1B, BMP type-1B receptor, BMPR-1B, CDw293, BMPR1B
Available
Primary Accession	O00238
Other Accession	P36898; Q05438; NP_001194
Antigen Type	Synthetic Peptide
Bio Background	The bone morphogenetic protein (BMP) receptors are a family of transmembrane serine/threonine kinases that include the type I receptors BMPR1A and BMPR1B and the type II receptor BMPR2. These receptors are also closely related to the activin receptors, ACVR1 and ACVR2. The ligands of these receptors are members of the TGF-beta superfamily. TGF-betas and activins transduce their signals through the formation of heteromeric complexes with 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding.
Bio References	Kan, L. et al. Stem Cells.January; 27(1): 150?56( 2009). Lehmann, K., et al., Proc. Natl. Acad. Sci. U.S.A. 100(21):12277-12282 (2003). Astrom, A.K., et al., Mamm. Genome 10(3):299-302 (1999). Ide, H., et al., Oncogene 14(11):1377-1382 (1997). ten Dijke, P., et al., Science 264(5155):101-104 (1994). Ide, H., et al., Cytogenet. Cell Genet. 81 (3-4), 285-286 (1998).
Gene ID	658
Gene Name	BMPR1B
Reactivity	H
Predicted	C, M
Calculated MW	56930
Antigen Region	472-502
Antigen Source	HUMAN
Target/Specificity	This BMPR1B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 472-502 amino acids from the C-terminal region of human BMPR1B.
NCBI Accession	NP_001194.1; NP_001243721.1; NP_001243722.1; NP_001243723.1

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Amount: 80 ul

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