Comparison

RPS6 Antibody (N-term)

Item no. ABC-AP20175a-ev-80ul
Manufacturer Abcepta
Amount 80 ul
Category
Type Antibody Polyclonal
Applications Western Blot
Specific against other
Host Rabbit
Isotype Ig
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias 40S ribosomal protein S6, Phosphoprotein NP33, RPS6
Available
Primary Accession
P62753
Other Accession
P62755; P62754; Q4R4K6; Q5E995; NP_001001.2
Antigen Type
Synthetic Peptide
Bio Background
Ribosomes, the organelles that catalyze protein synthesis,
consist of a small 40S subunit and a large 60S subunit. Together
these subunits are composed of 4 RNA species and approximately 80
structurally distinct proteins. This gene encodes a cytoplasmic
ribosomal protein that is a component of the 40S subunit. The
protein belongs to the S6E family of ribosomal proteins. It is the
major substrate of protein kinases in the ribosome, with subsets of
five C-terminal serine residues phosphorylated by different protein
kinases. Phosphorylation is induced by a wide range of stimuli,
including growth factors, tumor-promoting agents, and mitogens.
Dephosphorylation occurs at growth arrest. The protein may
contribute to the control of cell growth and proliferation through
the selective translation of particular classes of mRNA. As is
typical for genes encoding ribosomal proteins, there are multiple
processed pseudogenes of this gene dispersed through the genome.
Bio References
Maggi, L.B. Jr., et al. Mol. Cell. Biol. 28(23):7050-7065(2008)
Fujita, K., et al. Acta Neuropathol. 116(4):439-445(2008)
Robledo, S., et al. RNA 14(9):1918-1929(2008)
Glover, E.I., et al. Am. J. Physiol. Regul. Integr. Comp. Physiol. 295 (2), R604-R610 (2008) :
Ma, X.M., et al. Cell 133(2):303-313(2008)
Gene ID
6194
Gene Name
RPS6 {ECO:0000303|PubMed:29563586, ECO:0000312|HGNC:HGNC:10429}
Reactivity
H
Predicted
B, Pr, M, Rat
Calculated MW
28681
Antigen Region
1-30
Antigen Source
HUMAN
Target/Specificity
This RPS6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human RPS6.
NCBI Accession
NP_001001.2

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