« Back
Home /
Sqstm1(S351) Antibody

Sqstm1(S351) Antibody

Item no.	ABC-AP20690b
Manufacturer	Abcepta
Amount	400 ul
Category	Oncology Neuroscience Protein Aggregation, Clearance & Misfolding Antibodies By Cell Type Carcinoma Cell Biology Cell Status Adenocarcinoma Western Blot Autophagy Primary Antibodies
Type	Antibody Polyclonal
Applications	WB
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host	Rabbit
Isotype	IgG
Citations	Ishii T.,et al.Biochem. Biophys. Res. Commun. 226:456-460(1996). Morris J.C.,et al.Submitted (MAY-1996) to the EMBL/GenBank/DDBJ databases. Carninci P.,et al.Science 309:1559-1563(2005). Church D.M.,et al.PLoS Biol. 7:E1000112-E1000112(2009). Ishii T.,et al.Biochem. Biophys. Res. Commun. 232:33-37(1997).
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Sequestosome-1,STONE14,Ubiquitin-binding protein p62,Sqstm1,A170,STAP
Similar products	STAP, Sequestosome-1, Ubiquitin-binding protein p62, Sqstm1, A170, STONE14
Available
Manufacturer - Category	Crown Antibodies; Primary Antibodies; Antibody Collections; Cardiovascular; Signal Transduction; Phospho Antibodies
Manufacturer - Targets	This Phospho-Sqstm1(S351) antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 346-379 amino acids from the human region of human Phospho-Sqstm1(S351).
Bio Background	Required both for the formation and autophagic degradation of polyubiquitin-containing bodies, called ALIS (aggresome-like induced structures). Links ALIS to the autophagic machinery via direct interaction with MAP1 LC3 family members. May regulate the activation of NFKB1 by TNF-alpha, nerve growth factor (NGF) and interleukin-1. May play a role in titin/TTN downstream signaling in muscle cells. May regulate signaling cascades through ubiquitination. May be involved in cell differentiation, apoptosis, immune response and regulation of K(+) channels. Adapter that mediates the interaction between TRAF6 and CYLD.
Clonality	Polyclonal
Polyclonal Antibody Additonal Information	RB50742
Gene Name	Sqstm1 {ECO:0000303\|PubMed:16286508, ECO:0000312\|MGI:MGI:107931}
Subtitle	Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H, M
Predicted Reactivity	Rat
Calculated Molecular Weight	48163
Antigen Source	HUMAN
Formulation	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Dilution	WB: 1:1000

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

ABC-AP20690b-datasheet.pdf

Request safety datasheet

Simple Order Order Subscription

Amount: 400 ul

available

Delivery expected until 1/1/2026

Express Delivery: Save 8 days

Compare

Add to wishlist

Get an offer