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HUMAN-RIN1(Y36) Antibody

HUMAN-RIN1(Y36) Antibody

Item no.	ABC-AP20829a-ev-80ul
Manufacturer	Abcepta
Amount	80 ul
Category	Antibodies Western Blot Primary Antibodies
Type	Antibody Polyclonal
Applications	Western Blot
Specific against	other
Host	Rabbit
Isotype	Ig
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Ras and Rab interactor 1, Ras inhibitor JC99, Ras interaction/interference protein 1, RIN1
Available
Primary Accession	Q13671
Bio Background	Ras effector protein, which may serve as an inhibitory modulator of neuronal plasticity in aversive memory formation. Can affect Ras signaling at different levels. First, by competing with RAF1 protein for binding to activated Ras. Second, by enhancing signaling from ABL1 and ABL2, which regulate cytoskeletal remodeling. Third, by activating RAB5A, possibly by functioning as a guanine nucleotide exchange factor (GEF) for RAB5A, by exchanging bound GDP for free GTP, and facilitating Ras-activated receptor endocytosis.
Bio References	Colicelli J., et al.Proc. Natl. Acad. Sci. U.S.A. 88:2913-2917(1991). Han L., et al.Mol. Cell. Biol. 15:1318-1323(1995). Han L., et al.Proc. Natl. Acad. Sci. U.S.A. 94:4954-4959(1997). Afar D.E.H., et al.Immunity 6:773-782(1997). Tall G.G., et al.Dev. Cell 1:73-82(2001).
Gene ID	9610
Gene Name	RIN1
Reactivity	H
Calculated MW	84099
Antigen Source	HUMAN
Target/Specificity	This antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 20-70 amino acids from human.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 80 ul

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