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CYP24A1 Antibody (C-term)

CYP24A1 Antibody (C-term)

Item no.	ABC-AP21361b-ev-80ul
Manufacturer	Abcepta
Amount	80 ul
Category	Antibodies Western Blot Primary Antibodies
Type	Antibody Polyclonal
Applications	Western Blot
Specific against	other
Host	Rabbit
Isotype	Ig
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial, 24-OHase, Vitamin D(3) 24-hydroxylase, Cytochrome P450 24A1, Cytochrome P450-CC24, CYP24A1, CYP24
Available
Primary Accession	Q07973
Bio Background	Has a role in maintaining calcium homeostasis. Catalyzes the NADPH-dependent 24-hydroxylation of calcidiol (25- hydroxyvitamin D(3)) and calcitriol (1-alpha, 25-dihydroxyvitamin D(3)). The enzyme can perform up to 6 rounds of hydroxylation of calcitriol leading to calcitroic acid. It also shows 23- hydroxylating activity leading to 1-alpha, 25-dihydroxyvitamin D(3)-26, 23-lactone as end product.
Bio References	Chen K.-S., et al.Proc. Natl. Acad. Sci. U.S.A. 90:4543-4547(1993). Ren S., et al.J. Biol. Chem. 280:20604-20611(2005). Deloukas P., et al.Nature 414:865-871(2001). Chen K.-S., et al.Biochim. Biophys. Acta 1263:1-9(1995). Labuda M., et al.J. Bone Miner. Res. 8:1397-1406(1993).
Gene ID	1591
Gene Name	CYP24A1 (HGNC:2602)
Reactivity	H
Calculated MW	58875
Antigen Source	HUMAN
Target/Specificity	This CYP24A1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 480-514 amino acids from the C-terminal region of human CYP24A1.

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Amount: 80 ul

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