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MLF1 Antibody (C-term)

MLF1 Antibody (C-term)

Item no.	ABC-AP21370b-ev-80ul
Manufacturer	Abcepta
Amount	80 ul
Category	Oncology Antibodies Hematology Leukemia Western Blot Primary Antibodies Heart & Blood Cancer
Type	Antibody Polyclonal
Applications	Western Blot
Specific against	other
Host	Rabbit
Isotype	Ig
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Myeloid leukemia factor 1, Myelodysplasia-myeloid leukemia factor 1, MLF1
Available
Primary Accession	P58340
Bio Background	Involved in lineage commitment of primary hemopoietic progenitors by restricting erythroid formation and enhancing myeloid formation. Interferes with erythropoietin-induced erythroid terminal differentiation by preventing cells from exiting the cell cycle through suppression of CDKN1B/p27Kip1 levels. Suppresses RFWD2/COP1 activity via CSN3 which activates p53 and induces cell cycle arrest. Binds DNA and affects the expression of a number of genes so may function as a transcription factor in the nucleus.
Bio References	Yoneda-Kato N., et al.Oncogene 12:265-275(1996). Feng X., et al.Submitted (DEC-2004) to the EMBL/GenBank/DDBJ databases. Ota T., et al.Nat. Genet. 36:40-45(2004). Muzny D.M., et al.Nature 440:1194-1198(2006). Mural R.J., et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
Gene ID	4291
Gene Name	MLF1
Reactivity	H
Calculated MW	30627
Antigen Source	HUMAN
Target/Specificity	This MLF1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 216-250 amino acids from the C-terminal region of human MLF1.

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Amount: 80 ul

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