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NPRL3 Antibody (N-Term)

NPRL3 Antibody (N-Term)

Item no.	ABC-AP21877a
Manufacturer	Abcepta
Amount	200 ul
Category	Antibodies Primary Antibodies
Type	Antibody Primary
Format	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Applications	WB
Specific against	other
Host	Rabbit
Isotype	Ig
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	CGTHBA, NPRL3, Nitrogen permease regulator 3-like protein, -14 gene protein, Alpha-globin regulatory element-containing gene protein, Protein CGTHBA, C16orf35, MARE
Available
Primary Accession	Q12980
Application	WB
Bio Background	As a component of the GATOR1 complex, inhibitor of the amino acid-sensing branch of the TORC1 pathway. The GATOR1 complex strongly increases GTP hydrolysis by RRAGA and RRAGB within RRAGC- containing heterodimers, thereby deactivating RRAGs, releasing mTORC1 from lysosomal surface and inhibiting mTORC1 signaling.
Bio References	Vyas P., et al.Genomics 29:679-689(1995). De Gobbi M., et al.Science 312:1215-1217(2006). Martin J., et al.Nature 432:988-994(2004). Mural R.J., et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases. Neklesa T.K., et al.PLoS Genet. 5:E1000515-E1000515(2009).
Clonality	polyclonal
Clone/Animal Names	RB54296
Gene ID	8131
Gene Name	NPRL3 (HGNC:14124)
Subtitle	Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Legend image 1	Anti-NPRL3 Antibody (N-Term) at 1:2000 dilution + HT-1080 whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 64 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
Type image 1	WB
Dilution image 1	1:2000
Isotype	Rabbit Ig
Calculated MW	63605
Antigen Source	HUMAN
Target/Specificity	This NPRL3 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 86-117 amino acids from human NPRL3.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 200 ul

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Delivery expected until 9/4/2025

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