Comparison

ZNF238 Antibody (C-Term)

Item no. ABC-AP21938b-ev-50ul
Manufacturer Abcepta
Amount 50 ul
Category
Type Antibody Polyclonal
Applications Western Blot
Specific against other
Host Rabbit
Isotype Ig
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias Zinc finger and BTB domain-containing protein 18, 58 kDa repressor protein, Transcriptional repressor RP58, Translin-associated zinc finger protein 1, TAZ-1, Zinc finger protein 238, Zinc finger protein C2H2-171, ZBTB18, RP58, TAZ1, ZNF238
Available
Primary Accession
Q99592
Other Accession
Q9WUK6; Q9JKY3
Antigen Type
Synthesized Peptide
Bio Background
Transcriptional repressor that plays a role in various developmental processes such as myogenesis and brain development. Plays a key role in myogenesis by directly repressing the expression of ID2 and ID3, 2 inhibitors of skeletal myogenesis. Also involved in controlling cell division of progenitor cells and regulating the survival of postmitotic cortical neurons. Specifically binds the consensus DNA sequence 5'- [AC]ACATCTG[GT][AC]-3' which contains the E box core, and acts by recruiting chromatin remodeling multiprotein complexes. May also play a role in the organization of chromosomes in the nucleus.
Bio References
Becker K.G., et al.Hum. Mol. Genet. 4:685-691(1995).
Aoki K., et al.J. Biol. Chem. 273:26698-26704(1998).
Meng G., et al.Gene 242:59-64(2000).
Ota T., et al.Nat. Genet. 36:40-45(2004).
Gregory S.G., et al.Nature 441:315-321(2006).
Gene ID
10472
Gene Name
ZBTB18
Reactivity
M
Predicted
Rat
Calculated MW
58354
Antigen Source
HUMAN
Target/Specificity
This ZNF238 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 318-331 amino acids from human ZNF238.

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