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IGF2R Antibody (C-Term)

IGF2R Antibody (C-Term)

Item no.	ABC-AP21955b-ev-50ul
Manufacturer	Abcepta
Amount	50 ul
Category	Oncology Metabolism Diabetes Glucose Homeostasis Cholesterol & Lipid Metabolism Regulation of Appetite Antibodies Carcinoma Sarcoma Cell Biology Cell Culture Cytokines Western Blot Endocrine Regulation of Lipid Metabolism Primary Antibodies
Type	Antibody Polyclonal
Applications	Western Blot
Specific against	other
Host	Rabbit
Isotype	Ig
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Cation-independent mannose-6-phosphate receptor, CI Man-6-P receptor, CI-MPR, M6PR, 300 kDa mannose 6-phosphate receptor, MPR 300, Insulin-like growth factor 2 receptor, Insulin-like growth factor II receptor, IGF-II receptor, M6P/IGF2 receptor, M6P/IGF2R
Available
Primary Accession	P11717
Antigen Type	Synthesized Peptide
Bio Background	Transport of phosphorylated lysosomal enzymes from the Golgi complex and the cell surface to lysosomes. Lysosomal enzymes bearing phosphomannosyl residues bind specifically to mannose-6- phosphate receptors in the Golgi apparatus and the resulting receptor-ligand complex is transported to an acidic prelyosomal compartment where the low pH mediates the dissociation of the complex. This receptor also binds IGF2. Acts as a positive regulator of T-cell coactivation, by binding DPP4.
Bio References	Morgan D.O., et al.Nature 329:301-307(1987). Oshima A., et al.J. Biol. Chem. 263:2553-2562(1988). Gemma A., et al.Submitted (NOV-1998) to the EMBL/GenBank/DDBJ databases. Killian J.K., et al.Mamm. Genome 10:74-77(1999). Mungall A.J., et al.Nature 425:805-811(2003).
Gene ID	3482
Gene Name	IGF2R
Reactivity	H
Calculated MW	274375
Antigen Source	HUMAN
Target/Specificity	This IGF2R antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 2424-2458 amino acids from human IGF2R.

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Amount: 50 ul

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