Comparison

IGF2R Antibody (C-Term)

Item no. ABC-AP21955b-ev-50ul
Manufacturer Abcepta
Amount 50 ul
Category
Type Antibody Polyclonal
Applications Western Blot
Specific against other
Host Rabbit
Isotype Ig
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias Cation-independent mannose-6-phosphate receptor, CI Man-6-P receptor, CI-MPR, M6PR, 300 kDa mannose 6-phosphate receptor, MPR 300, Insulin-like growth factor 2 receptor, Insulin-like growth factor II receptor, IGF-II receptor, M6P/IGF2 receptor, M6P/IGF2R
Available
Primary Accession
P11717
Antigen Type
Synthesized Peptide
Bio Background
Transport of phosphorylated lysosomal enzymes from the Golgi complex and the cell surface to lysosomes. Lysosomal enzymes bearing phosphomannosyl residues bind specifically to mannose-6- phosphate receptors in the Golgi apparatus and the resulting receptor-ligand complex is transported to an acidic prelyosomal compartment where the low pH mediates the dissociation of the complex. This receptor also binds IGF2. Acts as a positive regulator of T-cell coactivation, by binding DPP4.
Bio References
Morgan D.O., et al.Nature 329:301-307(1987).
Oshima A., et al.J. Biol. Chem. 263:2553-2562(1988).
Gemma A., et al.Submitted (NOV-1998) to the EMBL/GenBank/DDBJ databases.
Killian J.K., et al.Mamm. Genome 10:74-77(1999).
Mungall A.J., et al.Nature 425:805-811(2003).
Gene ID
3482
Gene Name
IGF2R
Reactivity
H
Calculated MW
274375
Antigen Source
HUMAN
Target/Specificity
This IGF2R antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 2424-2458 amino acids from human IGF2R.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

 
Close