IL23A Antibody (Center)

Primary Antibodies; Cancer; Immunology; Microbiology; Antiviral defense; Immunity; Inflammatory response; Innate immunity; Immune system process; Cytokine; Interleukin signaling; Jak-STAT signaling KEGG

Associates with IL12B to form the IL-23 interleukin, a heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 may constitute with IL-17 an acute response to infection in peripheral tissues. IL-23 binds to a heterodimeric receptor complex composed of IL12RB1 and IL23R, activates the Jak- Stat signaling cascade, stimulates memory rather than naive T- cells and promotes production of proinflammatory cytokines. IL-23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tumorigenesis.

RB56752

Purified Rabbit Polyclonal Antibody (Pab)

20730

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Synthesized Peptide