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IRF8 Antibody (Center)

IRF8 Antibody (Center)

Item no.	ABC-AP2830c-ev
Manufacturer	Abcepta
Amount	80 ul
Category	Oncology Neuroscience Targets for Rodent Neurosciences Antibodies By Cell Type Melanoma Flow Cytometry Western Blot Primary Antibodies
Type	Antibody Polyclonal
Applications	WB, FC
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Citations	McGough,J.M., Mol. Cancer Res. 6 (12), 1841-1851 (2008) Tshuikina,M., Exp. Hematol. 36 (12), 1673-1681 (2008) Martinez,A., Am. J. Surg. Pathol. 32 (8), 1190-1200 (2008)
NCBI	NP_002154.1
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Interferon regulatory factor 8,IRF-8,Interferon consensus sequence-binding protein,H-ICSBP,ICSBP,IRF8,ICSBP1
Similar products	ICSBP, IRF8, H-ICSBP, ICSBP1, IRF-8, Interferon regulatory factor 8, Interferon consensus sequence-binding protein
Available
Manufacturer - Category	Primary Antibodies; Immunology; Catalog Updated
Manufacturer - Targets	This IRF8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 241-269 amino acids from the Central region of human IRF8.
Bio Background	Interferon consensus sequence-binding protein (ICSBP) is a transcription factor of the interferon (IFN) regulatory factor (IRF) family. Proteins of this family are composed of a conserved DNA-binding domain in the N-terminal region and a divergent C-terminal region that serves as the regulatory domain. The IRF family proteins bind to the IFN-stimulated response element (ISRE) and regulate expression of genes stimulated by type I IFNs, namely IFN-alpha and IFN-beta. IRF family proteins also control expression of IFN-alpha and IFN-beta-regulated genes that are induced by viral infection.
Clonality	Polyclonal
Polyclonal Antibody Additonal Information	RB17423
Gene Name	IRF8 {ECO:0000303\|PubMed:21524210, ECO:0000312\|HGNC:HGNC:5358}
Subtitle	Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Calculated Molecular Weight	48356
Antigen Source	HUMAN
Antigen Region	241-269
Formulation	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Dilution	WB: 1:1000 FC: 1:10~50
Antigen Type	Synthetic Peptide

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 80 ul

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