LCK Antibody (C-term)

Crown Antibodies; Primary Antibodies; Immunology; Signal Transduction; Anti-Kinome Antibodies; Viral process; Host-virus interaction; T cell activation; T cell receptor signaling

LCK is a member of the Src family of protein tyrosine kinases (PTKs). This protein is a key signaling molecule in the selection and maturation of developing T-cells. It contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. The protein localizes to the plasma membrane and pericentrosomal vesicles, and binds to cell surface receptors, including CD4 and CD8, and other signaling molecules.

RB17753

Purified Rabbit Polyclonal Antibody (Pab)

58001

480-509

WB: 1:1000
IHC-P: 1:50~100
FC: 1:10~50