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APEX1 Antibody (N-term)

APEX1 Antibody (N-term)

Item no.	ABC-AP2849a-ev
Manufacturer	Abcepta
Amount	80 ul
Category	Neuroscience Molecular Targets for Neuroscience Antibodies Western Blot Immunofluorescence Primary Antibodies
Type	Antibody Polyclonal
Applications	WB, IF
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Citations	Vascotto,C., Mol. Cell. Biol. 29 (7), 1834-1854 (2009) Li,W.Q., Carcinogenesis 30 (3), 500-505 (2009) Lo,Y.L., Cancer Epidemiol. Biomarkers Prev. 18 (1), 223-229 (2009) Bhakat,K.K., EMBO J. 22 (23), 6299-6309 (2003)
NCBI	NP_001231178.1,NP_001632.2,NP_542379.1,NP_542380.1
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	DNA-(apurinic or apyrimidinic site) lyase,31--,APEX nuclease,APEN,Apurinic-apyrimidinic endonuclease 1,AP endonuclease 1,APE-1,REF-1,Redox factor-1,DNA-(apurinic or apyrimidinic site) lyase,mitochondrial,APEX1,APE,APE1,APEX,APX,HAP1,REF1
Similar products	APE1, HAP1, APEX1, mitochondrial, APE, APEN, APEX, APX, REF1, DNA-(apurinic or apyrimidinic site) lyase, AP endonuclease 1, APE-1, APEX nuclease, Apurinic-apyrimidinic endonuclease 1, Redox factor-1, REF-1, 31--
Available
Manufacturer - Category	Primary Antibodies; Cardiovascular; Mitochondrion
Manufacturer - Targets	This APEX1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 30-64 amino acids from the N-terminal region of human APEX1.
Bio Background	Apurinic/apyrimidinic (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. AP sites are pre-mutagenic lesions that can prevent normal DNA replication so the cell contains systems to identify and repair such sites. Class II AP endonucleases cleave the phosphodiester backbone 5' to the AP site. This protein is the major AP endonuclease in human cells.
Clonality	Polyclonal
Polyclonal Antibody Additonal Information	RB17544
Gene Name	APEX1
Subtitle	Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Calculated Molecular Weight	35555
Antigen Source	HUMAN
Antigen Region	30-64
Formulation	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Dilution	IF: 1:10~50 WB: 1:1000 WB: 1:1000
Antigen Type	Synthetic Peptide

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 80 ul

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Delivery expected until 3/5/2026

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