Comparison

Phospho-CDK1(S39) Antibody

Item no. ABC-AP3059a-ev-80ul
Manufacturer Abcepta
Amount 80 ul
Category
Type Antibody Polyclonal
Applications Western Blot, Dot blot, Immunohistochemistry
Specific against other
Host Rabbit
Isotype Ig
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias Cyclin-dependent kinase 1, CDK1, Cell division control protein 2 homolog, Cell division protein kinase 1, p34 protein kinase, CDK1, CDC2, CDC28A, CDKN1, P34CDC2
Available
Primary Accession
P06493
Other Accession
P39951; P11440; P13863; P48734
Antigen Type
Synthetic Peptide
Bio Background
The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein is a catalytic subunit of the highly conserved protein kinase complex known as M-phase promoting factor (MPF), which is essential for G1/S and G2/M phase transitions of eukaryotic cell cycle. Mitotic cyclins stably associate with this protein and function as regulatory subunits. The kinase activity of this protein is controlled by cyclin accumulation and destruction through the cell cycle. The phosphorylation and dephosphorylation of this protein also play important regulatory roles in cell cycle control.
Bio References
Kramer, A., et al., Nat. Cell Biol. 6(9):884-891 (2004).
Dai, X., et al., J. Invest. Dermatol. 122(6):1356-1364 (2004).
Litvak, V., et al., Mol. Cell 14(3):319-330 (2004).
Shapira, M., et al., Cancer 100(8):1615-1621 (2004).
Chow, J.P., et al., J. Biol. Chem. 278(42):40815-40828 (2003).
Gene ID
983
Gene Name
CDK1
Reactivity
H
Predicted
B, C, M, Rat
Calculated MW
34095
Antigen Source
HUMAN
Target/Specificity
This CDK1 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S39 of human CDK1.
NCBI Accession
NP_001777.1; NP_203698.1

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