Comparison

Phospho-MET(Y1349) Antibody

Item no. ABC-AP3167a-ev-80ul
Manufacturer Abcepta
Amount 80 ul
Category
Type Antibody Polyclonal
Applications Western Blot, Immunohistochemistry
Specific against other
Host Rabbit
Isotype Ig
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias Hepatocyte growth factor receptor, HGF receptor, HGF/SF receptor, Proto-oncogene c-Met, Scatter factor receptor, SF receptor, Tyrosine-protein kinase Met, MET
Available
Primary Accession
P08581
Antigen Type
Synthetic Peptide
Bio Background
The proto-oncogene MET product is the hepatocyte growth factor receptor and encodes tyrosine-kinase activity. The primary single chain precursor protein is post-translationally cleaved to produce the alpha and beta subunits, which are disulfide linked to form the mature receptor. Various mutations in the MET gene are associated with papillary renal carcinoma.
Bio References
Wong, A.S., et al., Exp. Cell Res. 299(1):248-256 (2004).
Higuchi, T., et al., Mol. Cell. Biol. 24(17):7456-7468 (2004).
Mineo, R., et al., Endocrinology 145(9):4355-4365 (2004).
Chung, J., et al., J. Biol. Chem. 279(31):32287-32293 (2004).
Fischer, O.M., et al., J. Biol. Chem. 279(28):28970-28978 (2004).
Gene ID
4233
Gene Name
MET
Reactivity
H
Calculated MW
155541
Antigen Source
HUMAN
Target/Specificity
This MET Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Y1349 of human MET.
NCBI Accession
NP_000236.2; NP_001120972.1

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