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Bi-Phospho-Syk(Y525/526) Antibody

Bi-Phospho-Syk(Y525/526) Antibody

Item no.	ABC-AP3271a
Manufacturer	Abcepta
Amount	200 ul
Category	Oncology Antibodies By Cell Type Hematology Lymphoma Myeloma Immunohistochemistry Western Blot Primary Antibodies
Type	Antibody Polyclonal
Applications	WB, IHC-P
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Citations	Steinberg, M., et al., Blood 104(3):760-767 (2004). Wang, S., et al., World J. Gastroenterol. 10(12):1815-1818 (2004). Hayes, M.J., et al., Mol. Immunol. 41(4):457-468 (2004). Arndt, P.G., et al., J. Biol. Chem. 279(12):10883-10891 (2004). Ding, Y.B., et al., Zhonghua Yi Xue Za Zhi 84(4):290-293 (2004).
NCBI	NP_001128524.1,NP_001167638.1,NP_001167639.1,NP_003168.2
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Tyrosine-protein kinase SYK,Spleen tyrosine kinase,p72-Syk,SYK
Similar products	SYK, Tyrosine-protein kinase SYK, Spleen tyrosine kinase, p72-Syk
Available
Manufacturer - Category	Primary Antibodies; Antibody Collections; Cardiovascular; Immunology; Signal Transduction; Phospho Antibodies; Anti-Kinome Antibodies; Viral process; Host-virus interaction; Immunity; Inflammasome; Innate immunity; B cell receptor signaling; Fc gamma R-mediated phagocytosis
Manufacturer - Targets	This Syk Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Y525/526 of human Syk.
Bio Background	Syk is a positive effector of BCR-stimulated responses. This protein couples the B-cell antigen receptor (BCR) to the mobilization of calcium ion either through a phosphoinositide 3-kinase-dependent pathway, when not phosphorylated on tyrosines of the linker region, or through a phospholipase C-gamma-dependent pathway, when phosphorylated on Tyr-342 and Tyr-346. Thus the differential phosphorylation of Syk can determine the pathway by which BCR is coupled to the regulation of intracellular calcium ion.
Clonality	Polyclonal
Polyclonal Antibody Additonal Information	RB5669
Gene Name	SYK
Subtitle	Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Predicted Reactivity	M, Pig, Rat
Calculated Molecular Weight	72066
Antigen Source	HUMAN
Formulation	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Dilution	WB: 1:250 IHC-P: 1:50~100
Antigen Type	Synthetic Peptide

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 200 ul

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Delivery expected until 1/1/2026

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