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Phospho-TrkA(Y791) Antibody

Phospho-TrkA(Y791) Antibody

Item no.	ABC-AP3282a-ev
Manufacturer	Abcepta
Amount	80 ul
Category	Antibodies Primary Antibodies
Type	Antibody Primary
Format	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Applications	WB, Dot
Specific against	other
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	NTRK1, MTC, TRK, TRKA, High affinity nerve growth factor receptor, Neurotrophic tyrosine kinase receptor type 1, TRK1-transforming tyrosine kinase protein, Tropomyosin-related kinase A, Tyrosine kinase receptor, Tyrosine kinase receptor A, gp140trk, p140-TrkA, Trk-A
Available
Primary Accession	P04629
Antigen Type	Synthetic Peptide
Application	WB, DB
Bio Background	TrkA is a member of the neurotrophic tyrosine kinase receptor (NTKR) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in the TrkA gene have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, mental retardation and cancer.
Bio References	Tokusashi, Y., et al., Int. J. Cancer 114(1):39-45 (2005). Schulte, J.H., et al., Oncogene 24(1):165-177 (2005). Frattini, M., et al., Oncogene 23(44):7436-7440 (2004). Tacconelli, A., et al., Cancer Cell 6(4):347-360 (2004). Florenes, V.A., et al., Am. J. Clin. Pathol. 122(3):412-420 (2004).
Clonality	Polyclonal
Clone/Animal Names	RB16571, RB06984
Gene ID	4914
Gene Name	NTRK1
Subtitle	Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Legend image 1	Western blot analysis of lysates from A431 cell line, untreated or treated with EGF, 100ng/ml, using Phospho-TrkA(Y791) Antibody (Cat. #AP3282a)(upper) or Beta-Tubulin (lower).
Type image 1	WB
Dilution image 1	1:1000
Legend image 2	Dot blot analysis of anti-Phospho-TrkA-Y791 Pab (Cat.#AP3282a) on nitrocellulose membrane. 50ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. Antibody working concentrations are 0.5ug per ml.
Type image 2	DB
Dilution image 2	1:500
Isotype	Rabbit Ig
Calculated MW	87497
Antigen Source	HUMAN
Target/Specificity	This TrkA Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Y791 of human TrkA.
NCBI Accession	NP_001007793.1; NP_001012331.1; NP_002520.2

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 80 ul

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Delivery expected until 9/4/2025

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