Phospho-RPS6KB1(S418) Antibody

Primary Antibodies; Antibody Collections; Cancer; Cell Biology; Metabolism; Neuroscience; Signal Transduction; Phospho Antibodies; Fc gamma R-mediated phagocytosis; Mitochondrion; Mitochondrion outer membrane

This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 non-identical kinase catalytic domains and phosphorylates several residues of the S6 ribosomal protein. The kinase activity of this protein leads to an increase in protein synthesis and cell proliferation. Amplification of the region of DNA encoding this gene and overexpression of this kinase are seen in some breast cancer cell lines. Alternate translational start sites have been described and alternate transcriptional splice variants have been observed but have not been thoroughly characterized.

RB11399

Affinity Purified Rabbit Polyclonal Antibody (Pab)

B, M, Rb, Rat

HUMAN

DB: 1:500

Ribosomal protein S6 kinase beta-1, S6K-beta-1, S6K1, 70 kDa ribosomal protein S6 kinase 1, P70S6K1, p70-S6K 1, Ribosomal protein S6 kinase I, Serine/threonine-protein kinase 14A, p70 ribosomal S6 kinase alpha, p70 S6 kinase alpha, p70 S6K-alpha, p70 S6KA, RPS6KB1, STK14A