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Phospho-FRAP1(T2446) Antibody

Phospho-FRAP1(T2446) Antibody

Item no.	ABC-AP3433a
Manufacturer	Abcepta
Amount	400 ul
Category	Antibodies Primary Antibodies Dot Blot
Type	Antibody Polyclonal
Applications	Dot
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Citations	Dowling,R.J., Cancer Res. 67 (22), 10804-10812 (2007) Bai,X., Science 318 (5852), 977-980 (2007) Zhou,J., Proc. Natl. Acad. Sci. U.S.A. 104 (41), 16158-16163 (2007) Radulovic,S., J BUON 12 SUPPL 1, S151-S162 (2007)
NCBI	NP_004949.1
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	MTOR, mTOR, FRAP1, FRAP, FRAP2, RAFT1, RAPT1, Serine/threonine-protein kinase mTOR, FK506-binding protein 12-rapamycin complex-associated protein 1, FKBP12-rapamycin complex-associated protein, Mammalian target of rapamycin, Mechanistic target of rapamycin, Rapamycin and FKBP12 target 1, Rapamycin target protein 1
Available
Manufacturer - Category	Primary Antibodies; Antibody Collections; Cancer; Cardiovascular; Cell Biology; Metabolism; Phospho Antibodies; Interleukin signaling; Lysosome; Mitochondrion; Mitochondrion outer membrane
Manufacturer - Targets	This FRAP1 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding T2446 of human FRAP1.
Bio Background	FRAP1 belongs to a family of phosphatidylinositol kinase-related kinases. These kinases mediate cellular responses to stresses such as DNA damage and nutrient deprivation. This protein acts as the target for the cell-cycle arrest and immunosuppressive effects of the FKBP12-rapamycin complex. FRAP1 is a part of the TORC2 complex which plays a critical role in AKT1 Ser-473 phosphorylation, and may modulate the phosphorylation of PKCA and regulate actin cytoskeleton organization.
Clonality	Polyclonal
Polyclonal Antibody Additonal Information	RB13089
Gene Name	MTOR
Subtitle	Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Predicted Reactivity	M, Rat
Calculated Molecular Weight	288892
Antigen Source	HUMAN
Formulation	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Dilution	DB: 1:500
Antigen Type	Synthetic Peptide
Manufacturer - Alias	Serine/threonine-protein kinase mTOR, FK506-binding protein 12-rapamycin complex-associated protein 1, FKBP12-rapamycin complex-associated protein, Mammalian target of rapamycin, mTOR, Mechanistic target of rapamycin, Rapamycin and FKBP12 target 1, Rapamycin target protein 1, MTOR, FRAP, FRAP1, FRAP2, RAFT1, RAPT1
Manufacturer - Similar	Serine/threonine-protein kinase mTOR, FK506-binding protein 12-rapamycin complex-associated protein 1, FKBP12-rapamycin complex-associated protein, Mammalian target of rapamycin, mTOR, Mechanistic target of rapamycin, Rapamycin and FKBP12 target 1, Rapamycin target protein 1, MTOR, FRAP, FRAP1, FRAP2, RAFT1, RAPT1

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 400 ul

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Delivery expected until 1/1/2026

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