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Phospho-EIF4EBP1(S111) Antibody

Phospho-EIF4EBP1(S111) Antibody

Item no.	ABC-AP3473a-ev-80ul
Manufacturer	Abcepta
Amount	80 ul
Category	Metabolism Diabetes Glucose Homeostasis Cholesterol & Lipid Metabolism Regulation of Appetite Antibodies Endocrine Regulation of Lipid Metabolism Primary Antibodies Dot Blot
Type	Antibody Polyclonal
Applications	Dot blot
Specific against	other
Host	Rabbit
Isotype	Ig
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Eukaryotic translation initiation factor 4E-binding protein 1, 4E-BP1, eIF4E-binding protein 1, Phosphorylated heat- and acid-stable protein regulated by insulin 1, PHAS-I, EIF4EBP1
Available
Primary Accession	Q13541
Other Accession	Q62622; Q60876; NP_004086
Antigen Type	Synthetic Peptide
Bio Background	EIF4EBP1 is a member of a family of translation repressor proteins. This protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of EIF4EBP1 with eIF4E inhibits complex assembly and represses translation. EIF4EBP1 is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation.
Bio References	Fonseca, B.D., J. Biol. Chem. 282 (34), 24514-24524 (2007) Armengol, G., Cancer Res. 67 (16), 7551-7555 (2007)
Gene ID	1978
Gene Name	EIF4EBP1
Reactivity	H
Predicted	M, Rat
Calculated MW	12580
Antigen Source	HUMAN
Target/Specificity	This EIF4EBP1 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S111 of human EIF4EBP1.
NCBI Accession	NP_004086.1

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Amount: 80 ul

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