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Phospho-Raptor(S863) Antibody

Phospho-Raptor(S863) Antibody

Item no.	ABC-AP3495a
Manufacturer	Abcepta
Amount	400 ul
Category	Antibodies Immunohistochemistry Western Blot Primary Antibodies Dot Blot
Type	Antibody Polyclonal
Applications	WB, IHC-P, Dot
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Citations	Wang,Y., Circ. Res. 101 (6), 560-569 (2007) Fuchs,B.C., Am. J. Physiol., Cell Physiol. 293 (1), C55-C63 (2007) Olsen,J.V., Cell 127 (3), 635-648 (2006)
NCBI	NP_065812.1
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Regulatory-associated protein of mTOR,Raptor,p150 target of rapamycin (TOR)-scaffold protein,RPTOR,KIAA1303,RAPTOR
Similar products	Raptor, RPTOR, KIAA1303, RAPTOR, Regulatory-associated protein of mTOR, p150 target of rapamycin (TOR)-scaffold protein
Available
Manufacturer - Category	Primary Antibodies; Antibody Collections; Cell Biology; Signal Transduction; Phospho Antibodies; Lysosome
Manufacturer - Targets	This Raptor Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S863 of human Raptor.
Bio Background	Raptor participates in the FRAP1 pathway and associates in a near stoichiometric ratio with FRAP1 to form a nutrient-sensitive complex (NSC). It plays a pivotal role as a scaffold protein in the FRAP1-signaling pathway and this interaction is essential for the catalyzed phosphorylation of EIF4EBP1. It has a positive role in nutrient-stimulated signaling to the downstream effector RPS6KB1. Under nutrient-deprived conditions, raptor serves as a negative regulator of FRAP1 kinase activity. Regulation of the interaction with FRAP1 is a critical mechanism by which cells coordinate the rate of cell growth and maintenance of cell size with different environmental conditions.
Clonality	Polyclonal
Polyclonal Antibody Additonal Information	RB24817-24818
Gene Name	RPTOR
Subtitle	Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Calculated Molecular Weight	149038
Antigen Source	HUMAN
Formulation	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Dilution	WB: 1:500 IHC-P: 1:100 DB: 1:500
Antigen Type	Synthetic Peptide

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 400 ul

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Delivery expected until 1/1/2026

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