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Phospho-ANTXR1(Y382) Antibody

Phospho-ANTXR1(Y382) Antibody

Item no.	ABC-AP3547a
Manufacturer	Abcepta
Amount	400 ul
Category	Antibodies Primary Antibodies Dot Blot
Type	Antibody Polyclonal
Applications	Dot
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Citations	Werner,E., J. Biol. Chem. 281 (32), 23227-23236 (2006) Wei,W., Cell 124 (6), 1141-1154 (2006) Rainey,G.J., Proc. Natl. Acad. Sci. U.S.A. 102 (37), 13278-13283 (2005)
NCBI	NP_060623.2,NP_115584.1,NP_444262.1
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Anthrax toxin receptor 1,Tumor endothelial marker 8,ANTXR1,ATR,TEM8
Similar products	ATR, ANTXR1, TEM8, Anthrax toxin receptor 1, Tumor endothelial marker 8
Available
Manufacturer - Category	Primary Antibodies; Antibody Collections; Cardiovascular; Microbiology; Phospho Antibodies
Manufacturer - Targets	This ANTXR1 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Y382 of human ANTXR1.
Bio Background	ANTXR1 is a type I transmembrane protein and is a tumor-specific endothelial marker that has been implicated in colorectal cancer. This protein has been shown to also be a docking protein or receptor for Bacillus anthracis toxin, the causative agent of the disease, anthrax. The binding of the protective antigen (PA) component, of the tripartite anthrax toxin, to this receptor protein mediates delivery of toxin components to the cytosol of cells. Once inside the cell, the other two components of anthrax toxin, edema factor (EF) and lethal factor (LF) disrupt normal cellular processes.
Clonality	Polyclonal
Polyclonal Antibody Additonal Information	RB15324
Gene Name	ANTXR1 {ECO:0000303\|PubMed:22912819, ECO:0000312\|HGNC:HGNC:21014}
Subtitle	Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Predicted Reactivity	M, Rat
Calculated Molecular Weight	62789
Antigen Source	HUMAN
Formulation	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Dilution	DB: 1:500
Antigen Type	Synthetic Peptide

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 400 ul

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Delivery expected until 1/1/2026

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