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Phospho-IRS2(Y978) Antibody

Phospho-IRS2(Y978) Antibody

Item no.	ABC-AP3596a
Manufacturer	Abcepta
Amount	400 ul
Category	Antibodies Primary Antibodies
Type	Antibody Primary
Format	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Applications	Dot
Specific against	other
Host	Rabbit
Isotype	Ig
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	IRS-2, IRS2, Insulin receptor substrate 2
Available
Primary Accession	Q9Y4H2
Antigen Type	Synthetic Peptide
Application	DB
Bio Background	Insulin receptor substrate 2, a cytoplasmic signaling molecule that mediates effects of insulin, insulin-like growth factor 1, and other cytokines by acting as a molecular adaptor between diverse receptor tyrosine kinases and downstream effectors. This protein is phosphorylated by the insulin receptor tyrosine kinase upon receptor stimulation, as well as by an interleukin 4 receptor-associated kinase in response to IL4 treatment.
Bio References	Hagg, D.A., Int. J. Mol. Med. 21 (6), 697-704 (2008) Platanias, L.C., J. Biol. Chem. 271 (1), 278-282 (1996) Sun, X.J., Nature 377 (6545), 173-177 (1995)
Clonality	Polyclonal
Clone/Animal Names	RB15626
Gene ID	8660
Gene Name	IRS2
Subtitle	Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Legend image 1	Dot blot analysis of anti-Phospho-IRS2-pY978 Antibody (Cat.#AP3596a) on nitrocellulose membrane. 50ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. Antibody working concentrations are 0.5ug per ml.
Type image 1	DB
Dilution image 1	1:500
Other Accession	P81122
Predicted	M
Isotype	Rabbit Ig
Calculated MW	137334
Antigen Source	HUMAN
Target/Specificity	This IRS2 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Y978 of human IRS2.
NCBI Accession	NP_003740.2

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 400 ul

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Delivery expected until 11/6/2025

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