Phospho-LIMK1(Thr508)) Antibody

Primary Antibodies; Antibody Collections; Cancer; Neuroscience; Signal Transduction; Phospho Antibodies; Fc gamma R-mediated phagocytosis

There are approximately 4 known eukaryotic LIM proteins, so named for the LIM domains they contain. LIM domains are highlyconserved cysteine-rich structures containing 2 zinc fingers.Although zinc fingers usually function by binding to DNA or RNA, the LIM motif probably mediates protein-protein interactions. LIMkinase-1 and LIM kinase-2 belong to a small subfamily with a uniquecombination of 2 N-terminal LIM motifs and a C-terminal proteinkinase domain. LIMK1 is likely to be a component of anintracellular signaling pathway and may be involved in braindevelopment. LIMK1 hemizygosity is implicated in the impairedvisuospatial constructive cognition of Williams syndrome. [providedby RefSeq].

RB28259

Affinity Purified Rabbit Polyclonal Antibody (Pab)

72585

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Synthetic Peptide