Comparison

Phospho-MYH9(Y158) Antibody

Item no. ABC-AP3775a-ev-80ul
Manufacturer Abcepta
Amount 80 ul
Category
Type Antibody Polyclonal
Applications Dot blot
Specific against other
Host Rabbit
Isotype Ig
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias Myosin-9, Cellular myosin heavy chain, type A, Myosin heavy chain 9, Myosin heavy chain, non-muscle IIa, Non-muscle myosin heavy chain A, NMMHC-A, Non-muscle myosin heavy chain IIa, NMMHC II-a, NMMHC-IIA, MYH9
Available
Primary Accession
P35579
Other Accession
Q62812; Q8VDD5; P14105; NP_002464.1
Antigen Type
Synthetic Peptide
Bio Background
This gene encodes a myosin IIA heavy chain that contains an IQ domain and a myosin head-like domain. The protein is involved in several important functions, including cytokinesis, cell motility and maintenance of cell shape. Defects in MYH9 are the cause of non-syndromic sensorineural deafness autosomal dominant type 17, Epstein syndrome, Alport syndrome with macrothrombocytopenia, Sebastian syndrome, Fechtner syndrome and macrothrombocytopenia with progressive sensorineural deafness.
Bio References
Arii, J., et al. Nature 467(7317):859-862(2010)
Genovese, G., et al. Kidney Int. 78(7):698-704(2010)
Tzur, S., et al. Hum. Genet. 128(3):345-350(2010)
Bostrom, M.A., et al. Hum. Genet. 128(2):195-204(2010)
Oleksyk, T.K., et al. PLoS ONE 5 (7), E11474 (2010) :
Gene ID
4627
Gene Name
MYH9
Reactivity
H
Predicted
C, M, Rat
Calculated MW
226532
Antigen Source
HUMAN
Target/Specificity
This MYH9 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Y158 of human MYH9.
NCBI Accession
NP_002464.1

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