Comparison

Phospho-ULK1(S317) Antibody

Item no. ABC-AP3803a-ev-80ul
Manufacturer Abcepta
Amount 80 ul
Category
Type Antibody Polyclonal
Applications Dot blot
Specific against other
Host Rabbit
Isotype Ig
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias Serine/threonine-protein kinase ULK1, Autophagy-related protein 1 homolog, ATG1, hATG1, Unc-51-like kinase 1, ULK1, KIAA0722
Available
Primary Accession
O75385
Other Accession
NP_003556.1
Antigen Type
Synthetic Peptide
Bio Background
Involved in autophagy. Required for autophagosome formation (By similarity). Target of the TOR kinase signaling pathway that regulates autophagy through the control of phosphorylation status of ATG13/KIAA0652 and ULK1, and the regulation of the ATG13-ULK1-RB1CC1 complex (By similarity). Phosphorylates ATG13/KIAA0652. Involved in axon growth (By similarity). Plays an essential role in neurite extension of cerebellar granule cells (By similarity).
Bio References
Mercer, C.A., et al. Autophagy 5(5):649-662(2009) Ganley, I.G., et al. J. Biol. Chem. 284(18):12297-12305(2009) Jung, C.H., et al. Mol. Biol. Cell 20(7):1992-2003(2009) Hosokawa, N., et al. Mol. Biol. Cell 20(7):1981-1991(2009) Chan, E.Y. Sci Signal 2 (84), PE51 (2009) :
Gene ID
8408
Gene Name
ULK1
Reactivity
H
Calculated MW
112631
Antigen Source
HUMAN
Target/Specificity
This ULK1 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S317 of human ULK1.
NCBI Accession
NP_003556.1

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