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Phospho-ULK1(S556) Antibody

Phospho-ULK1(S556) Antibody

Item no.	ABC-AP3804a
Manufacturer	Abcepta
Amount	400 ul
Category	Antibodies Cell Biology Cell Status Immunofluorescence Autophagy Primary Antibodies Dot Blot
Type	Antibody Polyclonal
Applications	IF, Dot
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Citations	References for protein: 1.Mercer, C.A., et al. Autophagy 5(5):649-662(2009) 2.Ganley, I.G., et al. J. Biol. Chem. 284(18):12297-12305(2009) 3.Jung, C.H., et al. Mol. Biol. Cell 20(7):1992-2003(2009) 4.Hosokawa, N., et al. Mol. Biol. Cell 20(7):1981-1991(2009) 5.Chan, E.Y. Sci Signal 2 (84), PE51 (2009) References for U251 cell line: 1. Westermark B.; Pontén J.; Hugosson R. (1973).” Determinants for the establishment of permanent tissue culture lines from human gliomas”. Acta Pathol Microbiol Scand A. 81:791-805. [PMID: 4359449]. 2. Pontén, J.,Westermark B. (1978).” Properties of Human Malignant Glioma Cells in Vitro”. Medical Biology 56: 184-193.[PMID: 359950]. 3. Geng Y.;Kohli L.; Klocke B.J.; Roth K.A.(2010). “Chloroquine-induced autophagic vacuole accumulation and cell death in glioma cells is p53 independent”. Neuro Oncol. 12(5): 473–481.[ PMID: 20406898].
NCBI	NP_003556.1
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Serine/threonine-protein kinase ULK1,Autophagy-related protein 1 homolog,ATG1,hATG1,Unc-51-like kinase 1,ULK1,KIAA0722
Similar products	ATG1, hATG1, ULK1, KIAA0722, Serine/threonine-protein kinase ULK1, Autophagy-related protein 1 homolog, Unc-51-like kinase 1
Available
Manufacturer - Category	Primary Antibodies; Antibody Collections; Cardiovascular; Metabolism; Neuroscience; Signal Transduction; Autophagy; Phospho Antibodies; Autophagy; Regulation of autophagy
Manufacturer - Targets	This ULK1 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S556 of human ULK1.
Bio Background	Involved in autophagy. Required for autophagosome formation (By similarity). Target of the TOR kinase signaling pathway that regulates autophagy through the control of phosphorylation status of ATG13/KIAA652 and ULK1, and the regulation of the ATG13-ULK1-RB1CC1 complex (By similarity). Phosphorylates ATG13/KIAA652. Involved in axon growth (By similarity). Plays an essential role in neurite extension of cerebellar granule cells (By similarity).
Clonality	Polyclonal
Polyclonal Antibody Additonal Information	RB30585
Gene Name	ULK1 {ECO:0000303\|PubMed:9693035, ECO:0000312\|HGNC:HGNC:12558}
Subtitle	Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Calculated Molecular Weight	112631
Antigen Source	HUMAN
Formulation	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Dilution	IF: 1:200 DB: 1:500
Antigen Type	Synthetic Peptide

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 400 ul

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Delivery expected until 1/1/2026

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