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Phospho-mouse TSC1(T310) Antibody

Phospho-mouse TSC1(T310) Antibody

Item no.	ABC-AP3819a
Manufacturer	Abcepta
Amount	400 ul
Category	Oncology Antibodies By Cell Type Carcinoma Hematology Lymphoma Myeloma Adenocarcinoma Primary Antibodies Astrocytoma Dot Blot
Type	Antibody Polyclonal
Applications	Dot
Specific against	Mouse (Murine, Mus musculus)
Host	Rabbit
Isotype	IgG
Citations	Kladney, R.D., et al. Cancer Res. 70(21):8937-8947(2010) Sathaliyawala, T., et al. Immunity 33(4):597-606(2010) Scott, C.L., et al. Am. J. Physiol. Lung Cell Mol. Physiol. 299 (4), L455-L471 (2010): Bartolome, A., et al. Endocrinology 151(7):3084-3094(2010) Squarize, C.H., et al. PLoS ONE 5 (5), E10643 (2010) :
NCBI	NP_075025.2
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Hamartin,Tuberous sclerosis 1 protein homolog,Tsc1,Kiaa0243
Similar products	Hamartin, Tsc1, Kiaa0243, Tuberous sclerosis 1 protein homolog
Available
Manufacturer - Category	Primary Antibodies; Antibody Collections; Cancer; Cell Biology; Phospho Antibodies
Manufacturer - Targets	This mouse TSC1 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding T310 of mouse TSC1.
Bio Background	In complex with TSC2, inhibits the nutrient-mediated or growth factor-stimulated phosphorylation of S6K1 and EIF4EBP1 by negatively regulating mTORC1 signaling (By similarity). Implicated as a tumor suppressor. Involved in microtubule-mediated protein transport, but this seems to be due to unregulated mTOR signaling (By similarity).
Clonality	Polyclonal
Polyclonal Antibody Additonal Information	RB41244
Gene Name	Tsc1 {ECO:0000303\|PubMed:11130985, ECO:0000312\|MGI:MGI:1929183}
Subtitle	Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	M
Calculated Molecular Weight	128746
Antigen Source	MOUSE
Formulation	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Dilution	DB: 1:500
Antigen Type	Synthetic Peptide

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 400 ul

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Delivery expected until 1/1/2026

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