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Phospho-TSC2(S1096) Antibody

Phospho-TSC2(S1096) Antibody

Item no.	ABC-AP3898a-ev-80ul
Manufacturer	Abcepta
Amount	80 ul
Category	Oncology Antibodies Carcinoma Hematology Lymphoma Myeloma Primary Antibodies Astrocytoma Dot Blot
Type	Antibody Polyclonal
Applications	Dot blot
Specific against	other
Host	Rabbit
Isotype	Ig
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Tuberin, Tuberous sclerosis 2 protein, TSC2, TSC4
Available
Primary Accession	P49815
Other Accession	NP_000539.2
Antigen Type	Synthetic Peptide
Bio Background	Mutations in this gene lead to tuberous sclerosis complex. Its gene product is believed to be a tumor suppressor and is able to stimulate specific GTPases. The protein associates with hamartin in a cytosolic complex, possibly acting as a chaperone for hamartin. Alternative splicing results in multiple transcript variants encoding different isoforms.
Bio References	Slattery, M.L., et al. Carcinogenesis 31(9):1604-1611(2010) Larson, Y., et al. J. Biol. Chem. 285(32):24987-24998(2010) Mehta, M.S., et al. Breast Cancer Res. Treat. (2010) In press : Mieulet, V., et al. Trends Mol Med 16(7):329-335(2010) Liu, C.Y., et al. Carcinogenesis 31(7):1259-1263(2010)
Gene ID	7249
Gene Name	TSC2
Reactivity	H
Calculated MW	200608
Antigen Source	HUMAN
Target/Specificity	This TSC2 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S1096 of human TSC2.
NCBI Accession	NP_000539.2; NP_001070651.1; NP_001107854.1

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 80 ul

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