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Phospho-TSC2(S1388) Antibody

Phospho-TSC2(S1388) Antibody

Item no.	ABC-AP3899a
Manufacturer	Abcepta
Amount	400 ul
Category	Antibodies Primary Antibodies
Type	Antibody Primary
Format	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Applications	Dot
Specific against	other
Host	Rabbit
Isotype	Ig
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	TSC2, TSC4, Tuberin, Tuberous sclerosis 2 protein
Available
Primary Accession	P49815
Antigen Type	Synthetic Peptide
Application	DB
Bio Background	Mutations in this gene lead to tuberous sclerosis complex. Its gene product is believed to be a tumor suppressor and is able to stimulate specific GTPases. The protein associates with hamartin in a cytosolic complex, possibly acting as a chaperone for hamartin. Alternative splicing results in multiple transcript variants encoding different isoforms.
Bio References	Slattery, M.L., et al. Carcinogenesis 31(9):1604-1611(2010) Larson, Y., et al. J. Biol. Chem. 285(32):24987-24998(2010) Mehta, M.S., et al. Breast Cancer Res. Treat. (2010) In press : Mieulet, V., et al. Trends Mol Med 16(7):329-335(2010) Liu, C.Y., et al. Carcinogenesis 31(7):1259-1263(2010)
Clonality	Polyclonal
Clone/Animal Names	RB42384
Gene ID	7249
Gene Name	TSC2
Subtitle	Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Legend image 1	Dot blot analysis of TSC2 Antibody (Phospho S1388) Phospho-specific Pab (Cat. #AP3899a) on nitrocellulose membrane. 50ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. Antibody working concentrations are 0.6ug per ml.
Type image 1	DB
Dilution image 1	1:500
Other Accession	P49816; Q61037; NP_000539.2
Predicted	M, Rat
Isotype	Rabbit Ig
Calculated MW	200608
Antigen Source	HUMAN
Target/Specificity	This TSC2 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S1388 of human TSC2.
NCBI Accession	NP_000539.2; NP_001070651.1; NP_001107854.1

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 400 ul

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Delivery expected until 10/2/2025

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