Comparison

CD46 Antibody (C-term)

Item no. ABC-AP4785b-ev
Manufacturer Abcepta
Amount 80 ul
Category
Type Antibody Polyclonal
Applications WB, FC, IF, IHC-P
Specific against Human (Homo sapiens)
Host Rabbit
Isotype IgG
Citations Weyand, N.J., et al. J. Immunol. 184(2):694-701(2010)
Santiago, C., et al. Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun. 66 (PT 1), 91-94 (2010)
Sullivan, M., et al. Ann. Hum. Genet. 74(1):17-26(2010)
Lee, S.W., et al. J. Cell Biol. 156(6):951-957(2002)
NCBI NP_002380.3,NP_722548.1,NP_758860.1,NP_758861.1,NP_758862.1,NP_758863.1,NP_758869.1,NP_758871.1
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias Membrane cofactor protein,TLX,Trophoblast leukocyte common antigen,CD46,CD46,MCP,MIC10
Similar products CD46, MCP, TLX, MIC10, Membrane cofactor protein, Trophoblast leukocyte common antigen
Available
Manufacturer - Category
Crown Antibodies; Primary Antibodies; Immunology; Host cell receptor for virus entry; Viral entry into host cell; Host-virus interaction; Immunity; Innate immunity
Manufacturer - Targets
This CD46 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 317-343 amino acids from the C-terminal region of human CD46.
Bio Background
CD46 is a type I membrane protein and is a regulatory part of the complement system. The encoded protein has cofactor activity for inactivation of complement components C3b and C4b by serum factor I, which protects the host cell from damage by complement. In addition, the encoded protein can act as a receptor for the Edmonston strain of measles virus, human herpesvirus-6, and type IV pili of pathogenic Neisseria. Finally, the protein encoded by this gene may be involved in the fusion of the spermatozoa with the oocyte during fertilization. This gene is found in a cluster on chromosome 1q32 with other genes encoding structural components of the complement system.
Clonality
Polyclonal
Polyclonal Antibody Additonal Information
RB21743
Gene Name
CD46
Subtitle
Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity
H
Calculated Molecular Weight
43747
Antigen Source
HUMAN
Antigen Region
317-343
Formulation
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Dilution
IF: 1:10~50
WB: 1:1000
IHC-P: 1:50~100
FC: 1:10~50
Antigen Type
Synthetic Peptide

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 80 ul
Available: In stock
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