Comparison

RT33 Antibody (C-term)

Item no. ABC-AP5131b-ev-80ul
Manufacturer Abcepta
Amount 80 ul
Category
Type Antibody Polyclonal
Applications Western Blot, Flow cytometry, Immunohistochemistry
Specific against other
Host Rabbit
Isotype Ig
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias 28S ribosomal protein S33, mitochondrial, MRP-S33, S33mt, MRPS33
Available
Primary Accession
Q9Y291
Antigen Type
Synthetic Peptide
Bio Background
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. The 28S subunit of the mammalian mitoribosome may play a crucial and characteristic role in translation initiation. This gene encodes a 28S subunit protein that is one of the more highly conserved mitochondrial ribosomal proteins among mammals, Drosophila and C. elegans.
Bio References
Tsuritani, K., et al. Genome Res. 17(7):1005-1014(2007) Zhang, Z., et al. Genomics 81(5):468-480(2003) Cavdar Koc, E., et al. J. Biol. Chem. 276(22):19363-19374(2001)
Gene ID
51650
Gene Name
MRPS33
Reactivity
H, M
Calculated MW
12629
Antigen Region
72-100
Antigen Source
HUMAN
Target/Specificity
This RT33 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 72-100 amino acids from the C-terminal region of human RT33.
NCBI Accession
NP_057155.1; NP_444263.1

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