HABP2 Antibody (C-term)

NP_004123

HABP2 is an extracellular
serine protease that binds hyaluronic acid and is involved in cell
adhesion. The encoded protein is synthesized as a single chain, but
then undergoes an autoproteolytic event to form the functional
heterodimer. Further autoproteolysis leads to smaller, inactive
peptides. This protease is known to cleave urinary plasminogen
activator, coagulation factor VII, and the alpha and beta chains of
fibrinogen, but not prothrombin, plasminogen, or the gamma chain of
fibrinogen. Two transcript variants encoding different isoforms
have been found for this gene.

3026

H, M

378-408

This HABP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 378-408 amino acids from the C-terminal region of human HABP2.