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Leptin (LEP) Antibody (C-term)

Leptin (LEP) Antibody (C-term)

Item no.	ABC-AP6150a
Manufacturer	Abcepta
Amount	400 ul
Category	Antibodies Primary Antibodies
Type	Antibody Primary
Format	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Applications	WB, IF
Specific against	other
Host	Rabbit
Isotype	Ig
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	Leptin, LEP, OB, OBS, Obese protein, Obesity factor
Available
Primary Accession	P41159
Antigen Type	Synthetic Peptide
Application	WB, IF
Bio Background	Leptin (LEP) is an adipocyte-secreted protein that regulates body fat and endocrine functions. Leptin is similar to the mouse obesity protein encoded by the obese gene (ob). In mouse studies, mutations in this gene are linked to severe and morbid obesity.
Bio References	Tank, J., et al., J. Clin. Endocrinol. Metab. 88(10):4955-4959 (2003). Silha, J.V., et al., Eur. J. Endocrinol. 149(4):331-335 (2003). Kazumi, T., et al., Metab. Clin. Exp. 52(9):1113-1116 (2003). Mullington, J.M., et al., J. Neuroendocrinol. 15(9):851-854 (2003). Catalano, S., et al., J. Biol. Chem. 278(31):28668-28676 (2003).
Clonality	Polyclonal
Clone/Animal Names	RB2051
Gene ID	3952
Gene Name	LEP (HGNC:6553)
Subtitle	Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Legend image 1	Confocal immunofluorescent analysis of Leptin (LEP) Antibody (C-term)(Cat#AP6150a) with HepG2 cell followed by Alexa Fluor® 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).
Type image 1	IF
Dilution image 1	1:10~50
Legend image 2	Western blot analysis of hLep-R149 (Cat. #AP6150a) in MDA-MB231 cell line lysates (35ug/lane). LEP (arrow) was detected using the purified Pab.
Type image 2	WB
Dilution image 2	1:1000
Other Accession	NP_000221
Isotype	Rabbit Ig
Calculated MW	18641
Antigen Region	134-166
Antigen Source	HUMAN
Target/Specificity	This Leptin (LEP) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 134-166 amino acids from the C-terminal region of human Leptin (LEP).
NCBI Accession	NP_000221.1

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 400 ul

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Delivery expected until 9/4/2025

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