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MAGEA12 Antibody (N-term)

MAGEA12 Antibody (N-term)

Item no.	ABC-AP6162a-ev
Manufacturer	Abcepta
Amount	80 ul
Category	Antibodies Primary Antibodies
Type	Antibody Primary
Format	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Applications	WB, IHC-P
Specific against	other
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	MAGEA12, MAGE12, Melanoma-associated antigen 12, MAGE-12 antigen, MAGE12F antigen, CT112, Cancer/testis antigen 112
Available
Primary Accession	P43365
Antigen Type	Synthetic Peptide
Application	WB, IHC-P
Bio Background	MAGEA12 is a member of the melanoma antigen gene (MAGE) family. The proteins of this family are tumor-specific antigens that can be recognized by autologous cytolytic T lymphocytes. This gene is expressed in various tumors and tumor cell lines from different tissue origins, but not detected in normal tissues, except testis. The function of this gene is unknown. This and other MAGE genes form a gene cluster at chromosome Xq28 region.
Bio References	Mallon, A.M., et al., Genome Res. 10(6):758-775 (2000). Rogner, U.C., et al., Genomics 29(3):725-731 (1995). Ding, M., et al., Biochem. Biophys. Res. Commun. 202(1):549-555 (1994). De Smet, C., et al., Immunogenetics 39(2):121-129 (1994). De Plaen, E., et al., Immunogenetics 40(5):360-369 (1994).
Clonality	Polyclonal
Clone/Animal Names	RB2191
Gene ID	4111
Gene Name	MAGEA12
Subtitle	Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Legend image 1	MAGEA12 Antibody (S96) (Cat. #AP6162a) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the MAGEA12 antibody detected the MAGEA12 protein (arrow).
Type image 1	WB
Dilution image 1	1:1000
Legend image 2	MAGEA12 antibody (N-term) (Cat. #AP6162a)immunohistochemistry analysis in formalin fixed and paraffin embedded human breast carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of MAGEA12 antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.
Type image 2	IHC-P
Dilution image 2	1:10~50
Other Accession	NP_005358
Isotype	Rabbit Ig
Calculated MW	34836
Antigen Region	81-108
Antigen Source	HUMAN
Target/Specificity	This MAGEA12 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 81-108 amino acids from the N-terminal region of human MAGEA12.
NCBI Accession	NP_001159858.1; NP_001159859.1; NP_005358.2

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 80 ul

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Delivery expected until 9/4/2025

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