Comparison

MMP10 Antibody (C-term)

Item no. ABC-AP6194a
Manufacturer Abcepta
Amount 400 ul
Category
Type Antibody Primary
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Applications WB, IHC-P
Specific against other
Host Rabbit
Isotype Ig
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Similar products MMP10, STMY2, Stromelysin-2, Matrix metalloproteinase-10, Transin-2, MMP-10, SL-2
Available
Primary Accession
P09238
Antigen Type
Synthetic Peptide
Application
WB, IHC-P
Bio Background
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMPs are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. MMP10 degrades proteoglycans and fibronectin. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3.
Bio References
Nagase, H., et al., J. Biol. Chem. 274(31):21491-21494 (1999).
Pendas, A.M., et al., Genomics 37(2):266-268 (1996).
Jung, J.Y., et al., Ann. Genet. 33(1):21-23 (1990).
Sirum, K.L., et al., Biochemistry 28(22):8691-8698 (1989).
Muller, D., et al., Biochem. J. 253(1):187-192 (1988).
Clonality
Polyclonal
Clone/Animal Names
RB2022
Gene ID
4319
Gene Name
MMP10
Subtitle
Purified Rabbit Polyclonal Antibody (Pab)
Reactivity
H
Legend image 1
Western blot analysis of hMMP10-R409 (Cat. #AP6194a) in mouse spleen tissue lysates (35ug/lane). MMP10 (arrow) was detected using the purified Pab.
Type image 1
WB
Dilution image 1
1:1000
Legend image 2
Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
Type image 2
IHC-P
Dilution image 2
1:50~100
Other Accession
NP_002416
Isotype
Rabbit Ig
Calculated MW
54151
Antigen Region
394-423
Antigen Source
HUMAN
Target/Specificity
This MMP10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 394-423 amino acids from the C-terminal region of human MMP10.
NCBI Accession
NP_002416.1

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 400 ul
Available: In stock
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