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YBX1 Antibody (C-term)

YBX1 Antibody (C-term)

Item no.	ABC-AP6295B-ev-80ul
Manufacturer	Abcepta
Amount	80 ul
Category	Oncology Neuroscience Neural Development Antibodies Blastoma Western Blot Immunofluorescence Primary Antibodies
Type	Antibody Polyclonal
Applications	Immunofluorescence, Western Blot
Specific against	other
Host	Rabbit
Isotype	Ig
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Nuclease-sensitive element-binding protein 1, CCAAT-binding transcription factor I subunit A, CBF-A, DNA-binding protein B, DBPB, Enhancer factor I subunit A, EFI-A, Y-box transcription factor, Y-box-binding protein 1, YB-1, YBX1, NSEP1, YB1
Available
Primary Accession	P67809
Other Accession	P62961; P62960; P67808; Q00436
Antigen Type	Synthetic Peptide
Bio Background	YBX1 binds to splice sites in pre-mRNA and regulates splice site selection. This protein binds and stabilizes cytoplasmic mRNA and contributes to the regulation of translation by modulating the interaction between the mRNA and eukaryotic initiation factors. It binds to promoters that contain a Y-box (5'-CTGATTGGCCAA-3'), such as HLA class II genes. It regulates the transcription of numerous genes and promotes separation of DNA strands that contain mismatches or are modified by cisplatin. It has endonucleolytic activity and can introduce nicks or breaks into double-stranded DNA (in vitro), and it may play a role in DNA repair.
Bio References	Fujii, T., Cancer Res. 68 (5), 1504-1512 (2008) Fraser, D.J., Kidney Int. 73 (6), 724-732 (2008) Shiota, M., Cancer Res. 68 (1), 98-105 (2008)
Gene ID	4904
Gene Name	YBX1 (HGNC:8014)
Reactivity	H
Predicted	B, M, Rat
Calculated MW	35924
Antigen Region	276-305
Antigen Source	HUMAN
Target/Specificity	This YBX1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 276-305 amino acids from the C-terminal region of human YBX1.
NCBI Accession	NP_004550.2

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Amount: 80 ul

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