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TROP2 Antibody (Center)

TROP2 Antibody (Center)

Item no.	ABC-AP6681c-ev-80ul
Manufacturer	Abcepta
Amount	80 ul
Category	Oncology Antibodies Carcinoma Immunohistochemistry Western Blot Primary Antibodies
Type	Antibody Polyclonal
Applications	Western Blot, Immunohistochemistry
Specific against	other
Host	Rabbit
Isotype	Ig
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Tumor-associated calcium signal transducer 2, Cell surface glycoprotein Trop-2, Membrane component chromosome 1 surface marker 1, Pancreatic carcinoma marker protein GA733-1, TACSTD2, GA733-1, M1S1, TROP2
Available
Primary Accession	P09758
Antigen Type	Synthetic Peptide
Bio Background	TROP2 is a carcinoma-associated antigen defined by the monoclonal antibody GA733. This antigen is a member of a family including at least two type I membrane proteins. It transduces an intracellular calcium signal and acts as a cell surface receptor. Mutations of its gene result in gelatinous drop-like corneal dystrophy, an autosomal recessive disorder characterized by severe corneal amyloidosis leading to blindness.
Bio References	Goldstein, A.S., Proc. Natl. Acad. Sci. U.S.A. 105 (52), 20882-20887 (2008)
Gene ID	4070
Gene Name	TACSTD2
Reactivity	H
Calculated MW	35709
Antigen Region	162-190
Antigen Source	HUMAN
Target/Specificity	This TROP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 162-190 amino acids from the Central region of human TROP2.
NCBI Accession	NP_002344.2

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Amount: 80 ul

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