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CDC42 Antibody (Center)

CDC42 Antibody (Center)

Item no.	ABC-AP6934c
Manufacturer	Abcepta
Amount	400 ul
Category	Antibodies Flow Cytometry Western Blot Primary Antibodies
Type	Antibody Polyclonal
Applications	Western Blot, Flow cytometry
Specific against	other
Host	Rabbit
Isotype	Ig
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Available
Primary Accession	P60953
Subtitle	Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Other Accession	Q8CFN2, Q007T2, P60766, Q4R4R6, Q90694, Q2KJ93
Other Names	Cell division control protein 42 homolog, G25K GTP-binding protein, CDC42
Clone Names	RB21615
Antigen Type	Synthetic Peptide
Bio Background	CDC42 is a small GTPase of the Rho-subfamily, which regulates signaling pathways that control diverse cellular functions including cell morphology, migration, endocytosis and cell cycle progression. This protein is highly similar to Saccharomyces cerevisiae Cdc 42, and is able to complement the yeast cdc42-1 mutant. The product of oncogene Dbl was reported to specifically catalyze the dissociation of GDP from this protein. This protein could regulate actin polymerization through its direct binding to Neural Wiskott-Aldrich syndrome protein (N-WASP), which subsequently activates Arp2/3 complex.
Gene ID	998
Gene Name	CDC42
Calculated MW	21259
Antigen Region	106-134
Antigen Source	HUMAN
Target/Specificity	This CDC42 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 106-134 amino acids from the Central region of human CDC42.
Format	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
NCBI Accession	NP_001034891.1, NP_001782.1, NP_426359.1
Reactivity	H, M, Rat

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Amount: 400 ul

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