« Back
Home /
PKA C-beta (PRKACB) Antibody (N-term)

PKA C-beta (PRKACB) Antibody (N-term)

Item no.	ABC-AP7047a
Manufacturer	Abcepta
Amount	400 ul
Category	Antibodies Primary Antibodies
Type	Antibody Primary
Format	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Applications	WB, IHC-P
Specific against	other
Host	Rabbit
Isotype	Ig
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	PRKACB, cAMP-dependent protein kinase catalytic subunit beta, PKA C-beta
Available
Primary Accession	P22694
Antigen Type	Synthetic Peptide
Application	WB, IHC-P
Bio Background	cAMP is a signaling molecule important for a variety of cellular functions. cAMP exerts its effects by activating the cAMP-dependent protein kinase (AMPK), which transduces the signal through phosphorylation of different target proteins. The inactive holoenzyme of AMPK is a tetramer composed of two regulatory and two catalytic subunits. cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits. Four different regulatory subunits and three catalytic subunits of AMPK have been identified in humans. PRKACB is a member of the Ser/Thr protein kinase family and is a catalytic subunit of AMPK.
Bio References	Dwivedi, Y., et al., Biol. Psychiatry 55(3):234-243 (2004). Cartier, C., et al., J. Biol. Chem. 278(37):35211-35219 (2003). Higuchi, H., et al., EMBO J. 22(8):1790-1800 (2003). Wu, K.J., et al., Oncogene 21(51):7872-7882 (2002). Jiang, C.H., et al., Proc. Natl. Acad. Sci. U.S.A. 98(4):1930-1934 (2001).
Clonality	Polyclonal
Clone/Animal Names	RB3546
Gene ID	5567
Gene Name	PRKACB
Subtitle	Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Legend image 1	Anti-PRKACB Antibody (K29) at 1:1000 dilution + human brain lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 41 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
Type image 1	WB
Dilution image 1	1:1000
Legend image 2	Western blot analysis of PRKACB (arrow) using rabbit polyclonal PRKACB Antibody (K29) (Cat. #AP7047a). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the PRKACB gene.
Type image 2	WB
Dilution image 2	1:1000
Legend image 3	Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
Type image 3	IHC-P
Dilution image 3	1:50~100
Isotype	Rabbit Ig
Calculated MW	40623
Antigen Region	14-43
Antigen Source	HUMAN
Target/Specificity	This PKA C-beta (PRKACB) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 14-43 amino acids from the N-terminal region of human PKA C-beta (PRKACB).
NCBI Accession	NP_001229786.1; NP_001229787.1; NP_001229788.1; NP_001229789.1; NP_001229790.1; NP_001229791.1; NP_002722.1; NP_891993.1; NP_997461.1

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

ABC-AP7047a-datasheet.pdf

Request safety datasheet

Simple Order Order Subscription

Amount: 400 ul

available

Delivery expected until 11/6/2025

Express Delivery: Save 14 days

Compare

Add to wishlist

Get an offer