Comparison

CASK Antibody (C-term)

Item no. ABC-AP7212a
Manufacturer Abcepta
Amount 400 ul
Category
Type Antibody Primary
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Applications WB, IHC-P
Specific against other
Host Rabbit
Isotype Ig
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Similar products CASK, LIN2, Peripheral plasma membrane protein CASK, Calcium/calmodulin-dependent serine protein kinase, Protein lin-2 homolog, hCASK
Available
Primary Accession
O14936
Antigen Type
Synthetic Peptide
Application
IHC-P, WB
Bio Background
Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains.
The calcium/calmodulin-dependent kinase (CAMK) group consists of 75 kinases regulated by Ca2+/CaM and close relative family (CAMK, CAMKL, DAPK, MAPKAPK).
Bio References
Stevenson, D., et al., Mamm. Genome 11(10):934-937 (2000).
Cohen, A.R., et al., J. Cell Biol. 142(1):129-138 (1998).
Daniels, D.L., et al., Nat. Struct. Biol. 5(4):317-325 (1998).
Clonality
Polyclonal
Clone/Animal Names
RB1248
Gene ID
8573
Gene Name
CASK
Subtitle
Purified Rabbit Polyclonal Antibody (Pab)
Reactivity
H, M
Legend image 1
Western blot analysis of CASK (arrow) using Cask Antibody (C-term) (Cat.#AP7212a). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the CASK gene (Lane 2) (Origene Technologies).
Type image 1
WB
Dilution image 1
1:1000
Legend image 2
Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
Type image 2
IHC-P
Dilution image 2
1:50~100
Other Accession
Q62915; O70589
Predicted
Rat
Isotype
Rabbit Ig
Calculated MW
105123
Antigen Region
564-596
Antigen Source
HUMAN
Target/Specificity
This CASK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 564-596 amino acids from the C-terminal region of human CASK.
NCBI Accession
NP_001119526.1; NP_001119527.1; NP_003679.2

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 400 ul
Available: In stock
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