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MAPK11 Antibody (Center)

MAPK11 Antibody (Center)

Item no.	ABC-AP7223C
Manufacturer	Abcepta
Amount	400 ul
Category	Antibodies Primary Antibodies
Type	Antibody Primary
Format	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Applications	WB, IHC-P
Specific against	other
Host	Rabbit
Isotype	Ig
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	Mitogen-activated protein kinase 11, Mitogen-activated protein kinase p38 beta, MAPK11, PRKM11, SAPK2, SAPK2B, Stress-activated protein kinase 2b, p38-2, MAP kinase 11, MAPK 11, MAP kinase p38 beta, p38b, SAPK2b
Available
Primary Accession	Q15759
Antigen Type	Synthetic Peptide
Application	IHC-P, WB
Bio Background	MAPK11 is a Ser/Thr kinase involved in a signal transduction pathway that is activated by changes in the osmolarity of the extracellular environment, by cytokines, or by environmental stress. It preferentially phosphorylates transcription factor ATF2. This protein is activated by phosphorylation on threonine and tyrosine by MKK6, and is inhibited by pyridinyl-imidazole related compounds. Highest expression levels are in the brain and heart, with additional expression in the placenta, lung, liver, skeletal muscle, kidney and pancreas.
Bio References	Strausberg, R.L., et al., Proc. Natl. Acad. Sci. U.S.A. 99(26):16899-16903 (2002). Dunham, I., et al., Nature 402(6761):489-495 (1999). Enslen, H., et al., J. Biol. Chem. 273(3):1741-1748 (1998). Kumar, S., et al., Biochem. Biophys. Res. Commun. 235(3):533-538 (1997). Stein, B., et al., J. Biol. Chem. 272(31):19509-19517 (1997).
Clonality	Polyclonal
Clone/Animal Names	RB03193
Gene ID	5600
Gene Name	MAPK11
Subtitle	Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H, M
Legend image 1	Western blot analysis of anti-MAPK11 Pab (Cat. #AP7223c) in mouse brain tissue lysate. MAPK11 (arrow) was detected using purified Pab. Secondary HRP-anti-rabbit was used for signal visualization with chemiluminescence.
Type image 1	WB
Dilution image 1	1:1000
Legend image 2	Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
Type image 2	IHC-P
Dilution image 2	1:50~100
Isotype	Rabbit Ig
Calculated MW	41357
Antigen Region	334-366
Antigen Source	HUMAN
Target/Specificity	This MAPK11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 334-366 amino acids from the center region of human MAPK11.
NCBI Accession	NP_002742.3

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 400 ul

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Delivery expected until 11/6/2025

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