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MAPK1 Antibody (C-term)

MAPK1 Antibody (C-term)

Item no.	ABC-AP7250b
Manufacturer	Abcepta
Amount	400 ul
Category	Antibodies Primary Antibodies
Type	Antibody Primary
Format	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Applications	WB, FC, IHC-P
Specific against	other
Host	Rabbit
Isotype	Ig
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	MAPK1, ERK2, PRKM2, PRKM1, Mitogen-activated protein kinase 1, ERT1, Extracellular signal-regulated kinase 2, MAP kinase isoform p42, Mitogen-activated protein kinase 2, MAP kinase 1, MAPK 1, ERK-2, MAP kinase 2, MAPK 2, p42-MAPK
Available
Primary Accession	P28482
Antigen Type	Synthetic Peptide
Application	WB, FC, IHC-P
Bio Background	MAPK1 is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The activation of this kinase requires its phosphorylation by upstream kinases. Upon activation, this kinase translocates to the nucleus of the stimulated cells, where it phosphorylates nuclear targets.
Bio References	Munshi, H.G., et al., J. Biol. Chem. 279(37):39042-39050 (2004). Mukherjee, S., et al., Infect. Immun. 72(9):5274-5282 (2004). Lou, Y., et al., Biochem. Biophys. Res. Commun. 321(2):495-501 (2004). Mitsushima, M., et al., J. Biol. Chem. 279(33):34570-34577 (2004). Huang, H.M., et al., Biochem. Biophys. Res. Commun. 320(4):1247-1252 (2004).
Clonality	Polyclonal
Clone/Animal Names	RB11608
Gene ID	5594
Gene Name	MAPK1
Subtitle	Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Legend image 1	MAPK1 Antibody (C-term) (Cat.# AP7250b) western blot analysis in Hela cell line lysates (35ug/lane).This demonstrates the MAPK1 antibody detected the MAPK1 protein (arrow).
Type image 1	WB
Dilution image 1	1:1000
Legend image 2	Formalin-fixed and paraffin-embedded human breast carcinoma tissue reacted with MAPK1 Antibody (C-term)(Cat.#AP7250b), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Type image 2	IHC-P
Dilution image 2	1:50~100
Legend image 3	MAPK1 Antibody (C-term) (Cat. #AP7250b) flow cytometric analysis of HepG2 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Type image 3	FC
Dilution image 3	1:10~50
Other Accession	P63086; P63085; P46196
Predicted	B, M, Rat
Isotype	Rabbit Ig
Calculated MW	41390
Antigen Region	316-345
Antigen Source	HUMAN
Target/Specificity	This MAPK1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 316-345 amino acids from the C-terminal region of human MAPK1.
NCBI Accession	NP_002736.3; NP_620407.1

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 400 ul

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Delivery expected until 11/6/2025

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